Page 73 - CIBERSAM2016-ENG

Most relevant scientific articles
• Lanctôt KL, Agüera-Ortiz L, Brodaty H, Francis PT, Geda YE, Ismail Z et al. Apathy associated with neurocognitive disorders: recent progress and future directions.Alzheimer’s & dementia : the journal of the Alzheimer’s Association. 2016.
• Garcia Bueno B., Caso J.R., Madrigal J.L.M., Leza J.C. Innate immune receptor Toll-like receptor 4 signalling in neuropsychiatric diseases. Neuroscience and Biobehavioral Reviews. 2016; 64:134-147.
• España-Serrano L, Guerra Martín-Palanco N, Montero-Pedrazuela A, Pérez-Santamarina E, Vidal R, García-Consuegra I et al. The Addiction-Related Protein ANKK1 is Differentially Expressed During the Cell Cycle in Neural Precursors.Cerebral cortex (New York, N.Y.: 1991). 2016;.
• Marcos G., Santabarbara J., Lopez-Anton R., De-la-Camara C., Gracia-Garcia P., Lobo E. et al. Conversion to dementia in mild cognitive impairment diagnosed with DSM-5 criteria and with Petersen’s criteria. Acta Psychiatrica Scandinavica. 2016;133(5):378-385.
• Martin-Hernandez D., Caso J.R., Bris A.G., Maus S.R., Madrigal J.L.M., Garcia-Bueno B. et al. Bacterial translocation affects intracellular neuroinflammatory pathways in a depression-like model in rats. Neuropharmacology. 2016; 103:122-133.
Hightlights
The group G19 scientific activity is focused mainly on the molecular and genetic bases, neurocognition, neurophysiology, neuroinflammation and neuroimaging in psychiatric disorders. All these research lines are being financed through ongoing projects grants.
In 2016 we should highlight the creation of a new laboratory for molecular and genetic studies in psychiatric diseases. The opening of this laboratory will allow us to continue to deepen the functionality of the ANKK1 gene. These studies have result in several papers, the most recent being “The Addiction-Related Protein ANKK1 is Differentially Expressed During the Cell Cycle in Neural Precursors” published this year
in Cereb cortex. This new lab will allow us to continue the molecular studies of the dopaminergic system closely linked to the functionality of the ANKK1 gene.
In 2016, the IP of this G19 Group has established an institutional relationship with the San Carlos Sanitary Research Institute (IdISSC) as IP of the Psychiatric Disorders Group of the Institute. The 2017 Integrated Project of Excellence of Hospital Clinico de San Carlos, “Dysfunction of the coronary microcirculation, small vessel cerebral disease and depression in the patient with ischemic heart disease”, coordinated by the Cardiology Service, is a result of this collaboration.
The incorporation of Dr. Lobo to the group in Zaragoza has reinforced Dr. Agüera research in Madrid on dementia and cognition. This has resulted in a noticeable increase in the number of publications in this field by the group.
Our close collaboration with Dr. Leza’s group and other CIBERSAM groups is being very fruitful in the field of neuroinflammation with eight collaborative papers published in 2016.
Finally, with regard to teaching and training, we continue to coordinate the groups participating in the Interuniversity Master’s Degree in Mental Health Research at the Hospitals of Madrid.
SAM
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