Page 77 - CIBERSAM2016-ENG

• Personality disorders: mixed treatment in patients with Borderline Personality Disorder (BPD), validation of diagnostic instruments; genetic-environment studies; structural and functional neuroimaging studies on mindfulness effects; design and assessment of ICTs in the follow-up of BPD.
• Addictive Disorders: Patient satisfaction concerning maintenance treatment with opioid agonists (methadone and buprenorphine/naloxone); Methadone pharmacogenetics and satisfaction of heroin- dependent patients regarding methadone as a medication; explanatory factors of absence of cocaine craving throughout inpatient detoxification treatment; studies on the human reward circuit in abstinent cocaine- dependent patients.
• Mental health therapeutics: efficacy and resistance to treatment; validation of diagnostic and assessment scales; systematic reviews; neuropsychology; neurophysiology; neuroimaging and response to treatment.
New research lines:
• Adjuvant use of Ayahuasca in the treatment of Borderline Personality Disorder; Extreme phenotypes of treatment resistance in Depression; Prognostic study on treatment response prediction in Depression using PReDicT test; Analysis of clusters of cognitive performance in Depression and Schizophrenia; assessment of specific treatments in patients with bipolar disorder and history of trauma.
Most relevant scientific articles
• Vaquero L., Camara E., Sampedro F., Perez de los Cobos J., Batlle F., Fabregas J.M. et al. Cocaine addiction is associated with abnormal prefrontal function, increased striatal connectivity and sensitivity to monetary incentives, and decreased connectivity outside the human reward circuit. Addiction Biology. 2016.
• Serra-Blasco M., de Diego-Adelino J., Vives-Gilabert Y., Trujols J., Puigdemont D., Carceller-Sindreu M. et al. NATURALISTIC COURSE OF MAJOR DEPRESSIVE DISORDER PREDICTED BY CLINICAL AND STRUCTURAL NEUROIMAGING DATA: A 5-YEAR FOLLOW-UP. Depression and Anxiety. 2016.
• Martín-Blanco A, Ferrer M, Soler J, Arranz MJ, Vega D, Calvo N et al. The role of hypothalamus-pituitary- adrenal genes and childhood trauma in borderline personality disorder.European archives of psychiatry and clinical neuroscience. 2016;266(4):307-16.
• Davey C.G., Pujol J., Harrison B.J. Mapping the self in the brain’s default mode network. NeuroImage. 2016; 132:390-397.
• Pinho M., Sehmbi M., Cudney L.E., Kauer-Sant’anna M., Magalhaes P.V., Reinares M. et al. The association between biological rhythms, depression, and functioning in bipolar disorder: A large multi-center study. Acta Psychiatrica Scandinavica. 2016;133(2):102-108.
Hightlights
• Epigenetic study in patients with Borderline Personality Disorder.
• Clinical trial on the effects of mindfulness for the treatment of borderline personality disorder, assessed with
fMRI.
• Development and validation of a new technique for the temporal determination of cortisol in hair, as a
biomarker of stress and depression.
• Collaborative European project for the implementation of ICT in the prevention and treatment of
schizophrenia.
• Collaborative European and Spanish project on treatment response prediction using an algorithm based on
negative emotional bias.
• Publication of the first positive results on efficacy of deep brain estimulation in treatment-resistant
schizophrenia.
• Assessment of proneurones derived from the olfactory bulb as a model of mental disorders (Schizophrenia
research groups 77
and Major Depressive Disorder).
• Funding to conduct a clinical trial on Deep Brain Stimulation in treatment-resistant anorexia nervosa.
• Pilot study with S-Ketamine for treatment-resistant major depression.
SAM